http://pharmtech.findpharma.com/pharmtech A publication providing practical information on pharmaceutical manufacturing. Content focuses on applied R&D technology, process control and computer-integrated manufacturing, biotechnology and technical management. 2009-11-21T09:55:27Z http://pharmtech.findpharma.com/pharmtech/Rx-360-takes-on-Europe/ArticleStandard/Article/detail/642295?ref=25 The international pharmaceutical supply-chain consortium Rx-360 has launched in Europe; with more than 135 industry and regulatory representatives attending to discuss the global impact of counterfeit drug products. 2009-11-20T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/472009/642295null HTML http://pharmtech.findpharma.com/pharmtech/Manufacturing/Right-first-time-drug-manufacture/ArticleStandard/Article/detail/642528?ref=25 Engineers at a UK university claim to have developed technology that can be used in existing chemical reactors to ensure right first time drug crystal formation, which is crucial to their efficacy and the efficiency of pharmaceutical manufacturers' operations. 2009-11-20T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/472009/642528null HTML http://pharmtech.findpharma.com/pharmtech/Challenging-the-drug-development-blueprint-A-formu/ArticleStandard/Article/detail/643177?ref=25 Challenging the drug development blueprint: A formulator?s perspective - Sp Formulations Whitepaper 2009-11-20T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/472009/643177null PDF http://pharmtech.findpharma.com/pharmtech/50-of-MS-patients-avoid-treatment-over-injectable-/ArticleStandard/Article/detail/642529?ref=25 Around half of all multiple sclerosis (MS) patients that are eligible for treatment do not receive it and one in five of those patients that do begin therapy, delay doing so because of fear and anxiety over the treatment process, and not fear and anxiety about the disease. 2009-11-20T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/472009/642529null HTML http://pharmtech.findpharma.com/pharmtech/GSK-donates-flu-vaccine-to-the-WHO/ArticleStandard/Article/detail/642530?ref=25 GlaxoSmithKline (GSK) has agreed to donate 50 million doses of its adjuvanted pandemic influenza A (H1N1) vaccine to the World Health Organization (WHO). 2009-11-20T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/472009/642530null HTML http://pharmtech.findpharma.com/pharmtech/Pfizers-RampD-facility-consolidation/ArticleStandard/Article/detail/642533?ref=25 Following its $68-billion acquisition of Wyeth, Pfizer has unveiled detailed plans for its global R&D network, which includes consolidation of its R&D facilities. 2009-11-20T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/472009/642533null HTML http://pharmtech.findpharma.com/pharmtech/Manufacturing/Pfizer-Announces-RampD-Facility-Consolidation/ArticleStandard/Article/detail/642582?ref=25 Following the its $68-billion acquisition of Wyeth (Madison, NJ), Pfizer (New York) Pfizer detailed plans for its global research and development (R&D) network, which includes consolidation of its R&D facilities. 2009-11-19T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/472009/642582null HTML http://pharmtech.findpharma.com/pharmtech/News/Rx-360-Takes-on-Europe-Talks-to-PharmTech-About-Sh/ArticleStandard/Article/detail/642579?ref=25 The international pharmaceutical supply-chain consortium Rx-360 held a launch meeting in Europe last week with more than 135 industry and regulatory representatives in attendance. 2009-11-19T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/472009/642579null HTML http://pharmtech.findpharma.com/pharmtech/Manufacturing/GSK-Donates-Influenza-A-H1N1-Vaccine-to-WHO/ArticleStandard/Article/detail/642555?ref=25 Last week, GlaxoSmithKline (GSK, London) agreed to donate 50 million doses of its adjuvanted pandemic influenza A (H1N1) vaccine to the World Health Organization (WHO). 2009-11-19T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/472009/642555null HTML http://pharmtech.findpharma.com/pharmtech/Young-Innovators-Tempelate/ArticleStandard/Article/detail/643065?ref=25 2009-11-19T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/472009/643065null HTML http://pharmtech.findpharma.com/pharmtech/Drug+Delivery/Fifty-Percent-of-MS-Patients-Avoid-Treatment-Over-/ArticleStandard/Article/detail/642553?ref=25 Around half of all multiple sclerosis (MS) patients that are eligible for treatment do not receive it and one in five of those patients that do begin therapy, delay doing so because of fear and anxiety over the treatment process, and not fear and anxiety about the disease. 2009-11-19T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/472009/642553null HTML http://pharmtech.findpharma.com/pharmtech/Online+Only/Regulatory-Roundup-FDA-Expands-Use-of-CSLs-H1N1-Va/ArticleStandard/Article/detail/642580?ref=25 FDA has approved a fifth influenza A (H1N1) vaccine, manufactured by ID Biomedical. 2009-11-19T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/472009/642580null HTML http://pharmtech.findpharma.com/pharmtech/Analytics/Week-of-Nov-16-2009-GSK-and-Nabi-Form-Nicotine-Vac/ArticleStandard/Article/detail/642581?ref=25 Company and People Notes: Genzyme provides updates on enzyme replacement products and FDA complete response letter; Watson appoints VP of global operations; more... 2009-11-19T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/472009/642581null HTML http://pharmtech.findpharma.com/pharmtech/Editor%27s+Picks/November-2009-Editors-Picks-Products-from-Enercon-/ArticleStandard/Article/detail/641618?ref=25 PharmTech's monthly newsletter, Equipment & Processing Report, reviews the Editor's Picks for the November 2009 edition from Enercon and Schreiner. 2009-11-18T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/462009/641618null HTML http://pharmtech.findpharma.com/pharmtech/Online+Only/Are-Microreactors-Practical-for-Large-Scale-Produc/ArticleStandard/Article/detail/641595?ref=25 Recent advances in microreactor technology are improving the application and scale at which the technology can be applied. 2009-11-18T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/462009/641595null HTML http://pharmtech.findpharma.com/pharmtech/In+the+Mixer/Pigging-Can-Improve-Efficiency-and-Sustainability/ArticleStandard/Article/detail/641599?ref=25 Pigging is a sustainable strategy that can aid in cleaning and product recovery and improve a manufacturing line's efficiency and throughput. 2009-11-18T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/462009/641599null HTML http://pharmtech.findpharma.com/pharmtech/standard-terms-and-conditions/ArticleStandard/Article/detail/641975?ref=25 standard terms and conditions 2009-11-16T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/472009/641975null PDF http://pharmtech.findpharma.com/pharmtech/whitepaper-alert-sample/ArticleStandard/Article/detail/641968?ref=25 whitepaper sample 2009-11-16T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/472009/641968null PDF http://pharmtech.findpharma.com/pharmtech/Choosing-the-best-construction-material-for-powder/ArticleStandard/Article/detail/641571?ref=25 Choosing the best construction material for powder processing equipment - Freeman Whitepaper 2009-11-13T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/462009/641571null PDF http://pharmtech.findpharma.com/pharmtech/PharmTech-Europe-2010-media-kit/ArticleStandard/Article/detail/641620?ref=25 PharmTech Europe 2010 Media kit 2009-11-13T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/462009/641620null PDF http://pharmtech.findpharma.com/pharmtech/Protect-Your-Scientific-Intellectual-Property-Proo/ArticleStandard/Article/detail/641727?ref=25 Protect Your Scientific Intellectual Property: Proof of Lab Informatics Data Authenticity is Your Best Legal Defense - Surety Whitepaper 2009-11-13T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/462009/641727null PDF http://pharmtech.findpharma.com/pharmtech/Whitepapers/Protect-Your-Scientific-Intellectual-Property-Proo/ArticleStandard/Article/detail/641752?ref=25 As a pharmaceutical or biotechnology organization, your formulas, treatments and clinical findings are the "lifeblood" of your business. But if you aren't protecting the integrity of your scientific data in your lab informatics systems, you risk losing ownership, revenue and consequently your business if you can't prove time-of-creation and authenticity. Learn how you can implement simple, cost-effective, and automated controls to protect your scientific intellectual property. 2009-11-13T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/462009/641752null REMOTE http://pharmtech.findpharma.com/pharmtech/UK-backs-continuous-processing/ArticleStandard/Article/detail/639926?ref=25 A consortium led by GlaxoSmithKline (UK) intends to deliver a "step change improvement" in pharmaceutical tablet manufacturing in the UK by "substantially" increasing the country's manufacturing efficiency. 2009-11-13T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639926null HTML http://pharmtech.findpharma.com/pharmtech/Analytics/Choosing-the-best-construction-material-for-powder/ArticleStandard/Article/detail/641749?ref=25 Selecting the best material of construction is a crucial part of the plant design process, the aim being to balance performance and cost to best advantage. For powder processors, choosing a material that eases flow can pay dividends throughout the lifetime of the plant, but there is limited data on which to base this decision. A recent study by Freeman Technology highlights the role of the FT4 universal powder tester for such studies and provides some valuable comparative data for a wide range of commercially available materials and finishes. 2009-11-13T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/462009/641749null REMOTE http://pharmtech.findpharma.com/pharmtech/Regulation/EU-Issues-Strategy-for-Influenza-A-H1N1-Vaccine-Be/ArticleStandard/Article/detail/640749?ref=25 The European Medicines Agency, the European Center for Disease Prevention and Control, and the Heads of Medicines Agencies issued a European strategy for H1N1 vaccine benefit–risk monitoring. 2009-11-12T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/462009/640749null HTML http://pharmtech.findpharma.com/pharmtech/Manufacturing/Novartis-Updates-Vaccine-Progress-in-Germany-Acqui/ArticleStandard/Article/detail/640743?ref=25 Novartis reported that German regulatory authorities approved its adjuvanted cell culture-based Influenza A (H1N1) 2009 monovalent vaccine, Celtura. The company also said it will acquire a stake in Chinese vaccines company Zhejiang Tianyuan Bio-Pharmaceutical. 2009-11-12T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/462009/640743null HTML http://pharmtech.findpharma.com/pharmtech/Manufacturing/PhRMA-Reacts-to-House-Healthcare-Reform-Bill/ArticleStandard/Article/detail/640751?ref=25 On Sunday, Nov. 8, 2009, the Pharmaceutical Research and Manufacturers of America (PhRMA) expressed its disappointment with the US House of Representatives's healthcare-reform bill. 2009-11-12T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/462009/640751null HTML http://pharmtech.findpharma.com/pharmtech/Company+and+People+Notes/Week-of-Nov-9-2009-Merck-and-Schering-Plough-Begin/ArticleStandard/Article/detail/640959?ref=25 Company and People Notes: 3M forms agreement with VaxInnate; TRIN Pharma appoints CEO; More... 2009-11-12T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/462009/640959null HTML http://pharmtech.findpharma.com/pharmtech/Drug+Delivery/AAPS-Announces-Annual-Awards-Names-2009-Fellows/ArticleStandard/Article/detail/640909?ref=25 The American Association of Pharmaceutical Scientists (AAPS) recognized researchers at the organization's 2009 Annual Meeting and Exposition in Los Angeles this week. 2009-11-12T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/462009/640909null HTML http://pharmtech.findpharma.com/pharmtech/Online+Only/Regulatory-Roundup-FDA-Introduces-Safe-Use-Initiat/ArticleStandard/Article/detail/640917?ref=25 Also, Commissioner Hamburg addresses the nation's doctors in a letter about the influzenza A (H1N1) virus and vaccine. 2009-11-12T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/462009/640917null HTML http://pharmtech.findpharma.com/pharmtech/Manufacturing/UK-Backs-Continuous-Processing/ArticleStandard/Article/detail/640757?ref=25 A consortium led by GlaxoSmithKline (UK) intends to deliver a "step change improvement" in pharmaceutical tablet manufacturing in the UK by "substantially" increasing the country's manufacturing efficiency. 2009-11-12T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/462009/640757null HTML http://pharmtech.findpharma.com/pharmtech/CPhI-Exhibitors-Announce-Expansions/ArticleStandard/Article/detail/639790?ref=25 Exhibitors announce capacity expansions, service enhancements, and new products at CPhI Worldwide in Madrid. 2009-11-10T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639790null HTML http://pharmtech.findpharma.com/pharmtech/Sizing-Up-the-CDMO-Market/ArticleStandard/Article/detail/639786?ref=25 A new analysis highlights growth drivers and challenges for clinical supply-chain services. 2009-11-10T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639786null XML http://pharmtech.findpharma.com/pharmtech/Vetter-Expands-Clinical-and-Commercial-Scale-Opera/ArticleStandard/Article/detail/639783?ref=25 Vetter moves ahead with a new development facility in the US and expanded capabilities in Germany. 2009-11-10T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639783null HTML http://pharmtech.findpharma.com/pharmtech/Most+Viewed+Articles/Manufacturing-and-Regulatory-Considerations-in-Bio/ArticleStandard/Article/detail/639769?ref=25 Leading experts from an upcoming conference on biosimilars by the Drug, Chemical, and Associated Technologies Association share their insights on the manufacturing and regulatory considerations for biosimilars. 2009-11-10T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639769null HTML http://pharmtech.findpharma.com/pharmtech/Light-activated-gold-cage-delivery-capsule-develop/ArticleStandard/Article/detail/639156?ref=25 A smart nanocage that can be filled with a medicinal substance and then activated using light has been developed by US researchers. 2009-11-06T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639156null HTML http://pharmtech.findpharma.com/pharmtech/10-new-orphan-products-a-year-between-2009-and-201/ArticleStandard/Article/detail/639157?ref=25 The European Organisation for Rare Diseases (EURORDIS) has predicted that 100 new designated orphan products will receive marketing authorization between 2009 and 2019, which equates to approximately 10 new products every year. 2009-11-06T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639157null HTML http://pharmtech.findpharma.com/pharmtech/ICH-prepares-for-global-quality-implementation/ArticleStandard/Article/detail/639164?ref=25 The International Conference on Harmonization (ICH) has adopted pharmacopeial text annexes after a meeting of the steering committee and expert working groups last week. 2009-11-06T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639164null HTML http://pharmtech.findpharma.com/pharmtech/New-biopharm-pumps-with-extensive-documentation-pa/ArticleStandard/Article/detail/639925?ref=25 Alfa Laval has added two new biopharm pumps to its offering and can now meet a wider selection of customer needs at differentiated prices. 2009-11-06T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639925null HTML http://pharmtech.findpharma.com/pharmtech/USP-revises-excipient-standards-to-limit-contamina/ArticleStandard/Article/detail/639165?ref=25 In response to a request from the FDA, the US Pharmacopeial Convention (USP) has revised its standards for propylene glycol and sorbitol solution, excipients widely used in prescription and over-the-counter drugs. 2009-11-06T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639165null HTML http://pharmtech.findpharma.com/pharmtech/News/New-speciality-pharma-company-formed-in-Sweden/ArticleStandard/Article/detail/639927?ref=25 A new pharmaceutical company with a focus on rare diseases has been formed in Sweden following the merger of the Swedish companies Biovitrum and Swedish Orphan. 2009-11-06T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639927null HTML http://pharmtech.findpharma.com/pharmtech/Lonza-plans-cost-reductions/ArticleStandard/Article/detail/639163?ref=25 Lonza (Switzerland) has announced a series of cost-cutting measures for the next 12¬–18 months. 2009-11-06T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639163null HTML http://pharmtech.findpharma.com/pharmtech/SOCMA-petition-reveals-disparity-of-FDA-inspection/ArticleStandard/Article/detail/639161?ref=25 The FDA has responded to a citizen petition from the Society of Chemical Manufacturers and Affiliates (SOCMA) that highlighted the disparity in inspections of domestic and foreign drug-manufacturing facilities. 2009-11-06T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639161null HTML http://pharmtech.findpharma.com/pharmtech/Broken-biopharm/ArticleStandard/Article/detail/639155?ref=25 The engine of biopharmaceutical innovation is broken, according to Eli Lilly's Chairman and CEO, John C. Lechleiter. 2009-11-06T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639155null HTML http://pharmtech.findpharma.com/pharmtech/New-biopharm-portal-brings-clarity-to-equipment-GM/ArticleStandard/Article/detail/639915?ref=25 A site designed to take the mystery out of biopharm equipment selection, GMP concepts and good engineering practice. 2009-11-06T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639915null HTML http://pharmtech.findpharma.com/pharmtech/Most+Viewed+Articles/Illegal-equipment-puts-pharma-workers-in-danger/ArticleStandard/Article/detail/639158?ref=25 The prevalence of substandard or counterfeit safety products and personal protective equipment (PPE) has become a "very serious" problem in the UK, according to the British Safety Industry Federation (BSIF), and could be putting workers in the pharma industry at risk. 2009-11-06T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639158null HTML http://pharmtech.findpharma.com/pharmtech/Novartis-to-invest-1-billion-in-China-RampD-instit/ArticleStandard/Article/detail/639159?ref=25 Novartis (Switzerland) plans to invest $1 billion during the next 5 years to increase R&D activities in China, including a significant expansion of The Novartis Institute of BioMedical Research (CNIBR) in Shanghai. 2009-11-06T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639159null HTML http://pharmtech.findpharma.com/pharmtech/Analytics/Week-of-Nov-2-2009-Eli-Lilly-Opens-Biotech-Center-/ArticleStandard/Article/detail/639212?ref=25 Company and People Notes: sanofi aventis forms pact with Micromet; Laureate Pharma adds members to its business team. 2009-11-05T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639212null HTML http://pharmtech.findpharma.com/pharmtech/Manufacturing/Novartis-To-Invest-1-Billion-in-China-RampD-Instit/ArticleStandard/Article/detail/638992?ref=25 Novartis (Basel, Switzerland) plans to invest $1 billion over the next five years to increase research and development activities in China, including a significant expansion of The Novartis Institute of BioMedical Research (CNIBR) in Shanghai. 2009-11-05T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638992null HTML http://pharmtech.findpharma.com/pharmtech/Online+Only/Regulatory-Roundup-FDA-Issues-Guidance-on-In-Vitro/ArticleStandard/Article/detail/639001?ref=25 Also, FDA and WebMD increase collaboration and PPD is awarded contract to evaluate the agency's postmarket spontaneous-adverse-event surveillance system. 2009-11-05T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639001null HTML http://pharmtech.findpharma.com/pharmtech/Formulation/USP-Revises-Excipient-Standards-to-Limit-Contamina/ArticleStandard/Article/detail/639036?ref=25 In response to a request from the US Food and Drug Administration, the US Pharmacopeial Convention (USP) revised its standards for propylene glycol and sorbitol solution 2009-11-05T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639036null HTML http://pharmtech.findpharma.com/pharmtech/Ingredients/Lonza-Restructures-Plans-Cost-Reductions/ArticleStandard/Article/detail/639210?ref=25 Lonza (Basel, Switzerland), the large contract manufacturer of small-molecule and biologic-based active pharmaceutical ingredients (APIs), announced last week a series of cost-cutting measures for the next 12 to 18 months. 2009-11-05T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639210null HTML http://pharmtech.findpharma.com/pharmtech/Manufacturing/Europe-May-See-10-New-Orphan-Products-a-Year/ArticleStandard/Article/detail/638999?ref=25 The European Organization for Rare Diseases (EURORDIS) predicts that 100 new designated orphan products will receive marketing authorization between 2009 and 2019, which equates to approximately 10 new products every year. 2009-11-05T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638999null HTML http://pharmtech.findpharma.com/pharmtech/Ingredients/SOCMA-Hails-FDA-Action-on-Citizen-Petition-Regardi/ArticleStandard/Article/detail/639211?ref=25 The Society of Chemical Manufacturers and Affiliates (SOCMA) reported last week that the US Food and Drug Administration responded to the association's citizen petition relating to the inspection process of foreign drug-manufacturing facilities. 2009-11-05T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639211null HTML http://pharmtech.findpharma.com/pharmtech/Regulation/ICH-Adopts-Pharmacopeial-Text-Annexes-and-Prepares/ArticleStandard/Article/detail/638997?ref=25 Last week, the steering committee and expert working groups of the International Conference on Harmonization (ICH) met in St. Louis, Missouri. A major success of the meeting was the adoption of several annexes to ICH Q4B on pharmacopeial texts. 2009-11-05T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638997null HTML http://pharmtech.findpharma.com/pharmtech/Ingredients/Regulatory-Update-The-IPEC-Novel-Excipient-Safety-/ArticleStandard/Article/detail/639204?ref=25 The authors, representing the International Pharmaceutical Excipients Council, propose a new evaluation procedure, including tiered toxicology testing for excipients. 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639204null XML http://pharmtech.findpharma.com/pharmtech/IT/Stay-Afloat-with-Lessons-Learned/ArticleStandard/Article/detail/639195?ref=25 FDA's Edwin Rivera-Martinez on dodging supply-chain challenges. 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639195null XML http://pharmtech.findpharma.com/pharmtech/Ingredients+Insider/Advancing-Chiral-Chemistry-in-API-Synthesis/ArticleStandard/Article/detail/639207?ref=25 Functionalized supramolecular catalysts and an enantioselective route to unnatural amino acids are some recent developments. 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639207/pt-1109-p44-Ingredients_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639207null XML http://pharmtech.findpharma.com/pharmtech/Inside+Standards/Insider-Solutions-A-New-Direction-for-USP/ArticleStandard/Article/detail/639205?ref=25 With a five-yar revision cycle around the corner, USP will hit or miss the collaboration mark. 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639205null XML http://pharmtech.findpharma.com/pharmtech/IT/In-the-Spotlight/ArticleStandard/Article/detail/639200?ref=25 Editors' Picks of Pharmaceutical Science & Technology Innovations 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639200null XML http://pharmtech.findpharma.com/pharmtech/IT/DIY-Healthcare-Reform/ArticleStandard/Article/detail/639194?ref=25 While Congress debates hundreds of healthcare plan proposals, perhaps we, the public, can get in the game too. 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639194null XML http://pharmtech.findpharma.com/pharmtech/esolution-broadcast-2/ArticleStandard/Article/detail/638542?ref=25 esolution broadcast 2 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638542null PDF http://pharmtech.findpharma.com/pharmtech/Article/Moisture-Activated-Dry-GranulationmdashPart-I-A-Gu/ArticleStandard/Article/detail/639196?ref=25 The authors explain a process for moisture-activated dry granulation in detail and provide guidance for the selection of excipients and equipment. 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639196/pt1109-fig-1-P64B_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639196null XML http://pharmtech.findpharma.com/pharmtech/Article/Report-from-the-Philippines/ArticleStandard/Article/detail/639208?ref=25 New pricing controls and healthcare reforms may be pushing the pharmaceutical market out of this southeast Asian country. This article contains bonus online-exclusive material. 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639208/pt-1109-Philippines-p18_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639208/Bonus_main.gif http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639208null XML http://pharmtech.findpharma.com/pharmtech/Article/Changes-for-Better-or-Worse/ArticleStandard/Article/detail/639201?ref=25 New tests solve one issue, but cheaper plastic and new stoppers cause problems. 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639201null XML http://pharmtech.findpharma.com/pharmtech/Article/A-Robust-Automated-Karl-Fischer-Titration-System/ArticleStandard/Article/detail/639198?ref=25 The authors developed a robust, automated system to conduct Karl Fischer moisture assays for lyophilized products. 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639198/pt-1109-fig-2-p58B_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639198null XML http://pharmtech.findpharma.com/pharmtech/Article/Position-Paper-Are-We-Abandoning-IQ-and-OQ/ArticleStandard/Article/detail/639199?ref=25 The author explores differences between two qualification documents, the draft guidance from FDA "Process Validation: General Principles and Practice" and the ASTM E2500-7 standard "Guide for Specification, Design, and Verification of Pharmaceutical and Biopharmaceutical Manufacturing Systems and Equipment." 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639199/onlineEX_main.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639199null XML http://pharmtech.findpharma.com/pharmtech/Article/Are-We-Abandoning-IQ-and-OQ/ArticleStandard/Article/detail/639193?ref=25 New standards may overlook critical qualification needs. 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639193null XML http://pharmtech.findpharma.com/pharmtech/Ingredients/Sharing-Supply-Chain-Security/ArticleStandard/Article/detail/639209?ref=25 A panel of industry and regulatory experts, including FDA, discuss efforts to secure the global pharmaceutical supply chain. This article contains bonus online-exclusive material. 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639209/pt1109_coverstory_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639209/Bonus_main.gif http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639209null XML http://pharmtech.findpharma.com/pharmtech/Outsourcing+Outlook/Facing-Reality/ArticleStandard/Article/detail/639202?ref=25 Contract organizations waiting for the pipeline to come roaring back are kidding themselves. 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639202null XML http://pharmtech.findpharma.com/pharmtech/Industry+Leaders/Hans-Engels-of-DSM-Pharmaceuticals/ArticleStandard/Article/detail/639989?ref=25 Engels discusses the latest industry developments and trends. 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639989/P90.-Q&A_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639989null XML http://pharmtech.findpharma.com/pharmtech/whitepaper-alert/ArticleStandard/Article/detail/638549?ref=25 white paper alert 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638549null PDF http://pharmtech.findpharma.com/pharmtech/Article/Safety-versus-Speed-in-Drug-Development/ArticleStandard/Article/detail/639197?ref=25 The heightened focus on risk raises concerns about delays in approving new drugs. 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639197null XML http://pharmtech.findpharma.com/pharmtech/Ingredients/Whatever-Happened-to-Classical-Chemistry/ArticleStandard/Article/detail/639203?ref=25 A recent book reminds readers that small-molecule chemistry has enabled advances in biotechnology. 2009-11-02T05:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639203/pt-1109-Vetterlein-book-B_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639203/onlineEX_main.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/639203null XML http://pharmtech.findpharma.com/pharmtech/Analytics/Challenges-and-Strategies-for-Implementing-Automat/ArticleStandard/Article/detail/638760?ref=25 The authors used a light-transmission-based static division system to detect particles of foreign contaminants in prefilled vials. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638760/pt-1109supp-p25-fig1B_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638760null XML http://pharmtech.findpharma.com/pharmtech/Peer-Reviewed+Research/Developing-a-modified-Pulsincap-system/ArticleStandard/Article/detail/637638?ref=25 Chronotherapeutic drug delivery systems (CRDDS) have been recognized as potentially beneficial to the chronotherapy (timeoptimized therapy) of widespread chronic diseases that display time-dependent symptoms. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/637638/Patel_small_thumbnail.gif http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/637638null XML http://pharmtech.findpharma.com/pharmtech/Feature+Articles/Change-presents-an-opportunity-for-new-partnership/ArticleStandard/Article/detail/635590?ref=25 A meeting was recently held in Lindau, Germany, to discuss the changing face of pharma and biotech, and how companies can best prepare to face the challenges ahead. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/432009/635590/vetter_image_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/432009/635590null HTML http://pharmtech.findpharma.com/pharmtech/Industry+Leaders/Is-EU-pharma-ready-for-Braille-embossing/ArticleStandard/Article/detail/634891?ref=25 In 2010, Braille embossing will be required on all European pharmaceutical packages. Is the industry ready? 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/432009/634891/CraigJasper_thumb_thumbnail.gif http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/432009/634891null HTML http://pharmtech.findpharma.com/pharmtech/Drug+Delivery/Technology-Forecast-for-Injectables/ArticleStandard/Article/detail/638759?ref=25 A Conversation with Greystone Associates' George Perros. This article contains bonus online-exclusive material. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638759/pt1109-sup-needles-CV-B_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638759/Bonus_main.gif http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638759null XML http://pharmtech.findpharma.com/pharmtech/Ingredients/Targeting-Therapeutics-for-the-Middle-and-Inner-Ea/ArticleStandard/Article/detail/638761?ref=25 A Conversation with Otonomy 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638761/pt1109-sup-needles-CV-B_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638761null XML http://pharmtech.findpharma.com/pharmtech/Formulation/Current-Perspectives-on-Aseptic-Formulations/ArticleStandard/Article/detail/638763?ref=25 The author details the factors in formulation design, requirements in facilites and equipment, and validation criteria for aseptic formualtions. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638763/pt1109-sup-needles-CV-B_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638763null XML http://pharmtech.findpharma.com/pharmtech/Editor%27s+comment/Have-your-say/ArticleStandard/Article/detail/637630?ref=25 November is finally upon us and the days are getting colder and shorter. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/637630null XML http://pharmtech.findpharma.com/pharmtech/Industry+Leaders/Preventing-counterfeits-from-entering-the-supply-c/ArticleStandard/Article/detail/635815?ref=25 With counterfeit drugs on the rise, the Chairman and CEO of Ahura Scientific discusses the issue and explains how a handheld device is helping companies to tackle the problem. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/432009/635815/doug_thumbnail_thumbnail.gif http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/432009/635815null HTML http://pharmtech.findpharma.com/pharmtech/News/ArticleStandard/Article/detail/637631?ref=25 A round-up of news from across the industry. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/637631null XML http://pharmtech.findpharma.com/pharmtech/Industry+Leaders/A-novel-drug-detection-technology/ArticleStandard/Article/detail/631248?ref=25 Researchers at the University of Leicester (UK) have combined crime research and space-age technology to create a new method of detecting counterfeit pharmaceuticals. The technique, Spectral ID, works by detecting the differences between the characteristics of light reflected from printed packaging. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/412009/631248null HTML http://pharmtech.findpharma.com/pharmtech/Manufacturing/Sustainability-in-the-packaging-supply-chain/ArticleStandard/Article/detail/631118?ref=25 Michael Rubenstein, Chief Growth and Innovation Officer at Alcan Packaging, talks about applying a philosophy of sustainability to the pharmaceutical packaging supply chain. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/402009/631118null HTML http://pharmtech.findpharma.com/pharmtech/IT/Simplifying-data-management/ArticleStandard/Article/detail/637637?ref=25 Paper is no longer a sufficient format for information storage and interchange in the pharmaceutical industry; documents are inflexible and costly for production and storage. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/637637null XML http://pharmtech.findpharma.com/pharmtech/Drug+Delivery/Case-study-printing-powders-with-Sticky-Web-techno/ArticleStandard/Article/detail/637639?ref=25 GlaxoSmithKline (GSK) appointed 42 Technology (42T) to evaluate existing powder dispensing approaches that could be scaled for high speed manufacturing. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/637639/CaseStudy_small_thumbnail.gif http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/637639/CaseStudy_flash.jpg XML http://pharmtech.findpharma.com/pharmtech/Drug+Delivery/Regulatory-challenges-of-inhaler-testing/ArticleStandard/Article/detail/636406?ref=25 Mark Copley discusses the methods used for DPI testing and the challenges presented by the current regulatory framework. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/636406/Inhaler_web_thumbnail.gif http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/636406null HTML http://pharmtech.findpharma.com/pharmtech/Regulation/USPs-Ferrules-and-Caps-Labeling-Changes-Put-on-Hol/ArticleStandard/Article/detail/638764?ref=25 This article provides an update to the author's Viewpoint column, "Changes to Vial Labels May Affect Patient Safety," which ran in Pharmaceutical Technology's March 2009 issue. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638764/pt1109-sup-needles-CV-B_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638764null XML http://pharmtech.findpharma.com/pharmtech/Industry+Leaders/Neal-Dunkinson-151-Up-to-date-business-planning/ArticleStandard/Article/detail/634870?ref=25 Neal Dunkinson, Commercial Development Manager at CMR International, Thomson Reuters talks about the 2009 Edition of the CMR International Pharmaceutical R&D Factbook. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/432009/634870/thumbnail_thumbnail.gif http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/432009/634870null HTML http://pharmtech.findpharma.com/pharmtech/Manufacturing/Demographic-time-bomb/ArticleStandard/Article/detail/637635?ref=25 Population ageing is an issue often discussed in the media, but its impact on all facets of life has been poorly characterized. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/637635null XML http://pharmtech.findpharma.com/pharmtech/Packaging+%26+Labeling/Packaging-the-experts-view/ArticleStandard/Article/detail/637634?ref=25 What trends have you witnessed in the pharmaceutical packaging industry in the last 2 years? 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/637634/Q_small_thumbnail.gif http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/637634null XML http://pharmtech.findpharma.com/pharmtech/Outsourcing/Reality-not-insanity/ArticleStandard/Article/detail/637636?ref=25 Apopular definition of insanity is repeating the same task over and over again while expecting a different result. It would appear, therefore, that many people in the contract services industry think the major global bio/pharma companies are insane. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/637636null XML http://pharmtech.findpharma.com/pharmtech/Packaging+%26+Labeling/The-pharmaceutical-packaging-market/ArticleStandard/Article/detail/637640?ref=25 According to a survey conducted by Pharmaceutical Technology Europe (PTE), almost 50% of you believe that cost is the biggest limiting factor to innovation in the pharmaceutical packaging industry. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/637640/OpenArticle_small_thumbnail.gif http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/637640null XML http://pharmtech.findpharma.com/pharmtech/Drug+Delivery/From-Needle-to-Pill-Reformulating-Injectable-Drugs/ArticleStandard/Article/detail/638762?ref=25 The author describes how Merrion Pharmaceuticals reformulates parenteral drugs into tablets and capsules that are easier for patients to take and provide better bioavailability. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638762/pt1109-sup-needles-CV-B_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638762null XML http://pharmtech.findpharma.com/pharmtech/Drug+Delivery/Risk-Management-for-Aseptic-Processing/ArticleStandard/Article/detail/638758?ref=25 The author discusses the risks involved with aseptic processing, methods and tools used to identify and control risk, and regulatory guidelines relevant to the risk-management process. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638758/pt1109-sup-needles-CV-B_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638758null XML http://pharmtech.findpharma.com/pharmtech/Packaging+%26+Labeling/Plastic-Prefilled-Syringes-A-Better-Fit-for-Autoin/ArticleStandard/Article/detail/638757?ref=25 The authors describe the ways in which plastic prefilled syringes can be an alternative that provides consistent performance, protects drugs prone to degradation, and enhances patient safety. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638757/pt-1109-sup-fig-1-p7B_thumbnail.jpg http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/452009/638757null XML http://pharmtech.findpharma.com/pharmtech/Packaging+%26+Labeling/Trends-in-labelling/ArticleStandard/Article/detail/637632?ref=25 Following years of development, DataMatrix codes are now a viable labelling solution for pharma manufacturers. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/637632/Beauchamp_small_thumbnail.gif http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/442009/637632null XML http://pharmtech.findpharma.com/pharmtech/Peter-Soelkner-of-Vetter/ArticleStandard/Article/detail/635816?ref=25 Peter Soelkner discusses Vetter?s commitment to its clients and the 2nd Vetter Drug Management Leadership Conference, 23–24 September 2009, Lindau, Germany. 2009-11-01T04:00:00Z http://pharmtech.findpharma.com/pharmtech/data/articlestandard/pharmtech/432009/635816null HTML